A case of bronchial asthma and dermatitis due to spiramycin is described in a non-atopic woman who worked as a chick breeder and handling poultry feed containing antibiotic or chemoterapic drugs including spiramycin, chlortetracycline and sulfadimethoxine. Patch tests showed a vigorous delayed reaction to spiramycin....
This case suggests that allergic reactions to a chemical product may involve both type III and IV hypersensitivity.
http://www3.interscience.wiley.com/journal/119607052/abstract?CRETRY=1&SRETRY=0
Critical assessments of the evidence for agents implicated in occupational asthma
SECTION C: The following substances were considered to meet the new EU criteria, revised in 1996, for classification as a respiratory sensitiser (a cause of asthma) and labelling with R42
In 1993 the Health and Safety Commission (HSC) identified six health concerns related to occupational exposure to chemicals as priorities for action, one of which was occupational asthma (asthma caused by occupation). A number of sources of information show that occupational asthma, resulting from the inhalation of certain chemicals and other agents in the workplace, has become a major category of work-related respiratory ill-health in the UK.
http://www.hse.gov.uk/asthma/asthmagen.pdf
Antibiotics are accepted by the medical profession as causing asthma - albeit 'professional asthma' through inhalation during manufacture in the...
oem.bmj.com/cgi/eletters/64/1/37
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Workers manufacturing antibiotics can get compensation if they become asthmatic. The medical profession calls this professional asthma.. 再生時間：01:19...
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Occupational asthma specific to amoxicillin
http://www3.interscience.wiley.com/journal/119115601/abstract?CRETRY=1&SRETRY=0